{"id":701,"date":"2020-04-07T11:07:33","date_gmt":"2020-04-07T05:37:33","guid":{"rendered":"http:\/\/www.potentialloops.org\/?p=701"},"modified":"2020-04-07T11:07:34","modified_gmt":"2020-04-07T05:37:34","slug":"possible-coronavirus-drug-identified","status":"publish","type":"post","link":"https:\/\/www.potentialloops.org\/?p=701","title":{"rendered":"Possible coronavirus drug identified"},"content":{"rendered":"\n

Ivermectin stops SARS-CoV-2 virus growing in cell culture <\/h4>\n\n\n\n

Date: April 3, 2020 <\/p>\n\n\n\n

Source 1: Monash University <\/p>\n\n\n\n

Source 2 : www.sciencedaily.com<\/a><\/p>\n\n\n\n

Summary: A new study has shown that an anti-parasitic drug already available around the world can kill the virus within 48 hours. Scientists found that a single dose of the drug, Ivermectin, could stop the SARS-CoV-2 virus growing in cell culture. The next steps are to determine the correct human dosage — ensuring the doses shown to effectively treat the virus in vitro are safe for humans. <\/p>\n\n\n\n

\"\"
Source: Google images, 7news.com.au<\/figcaption><\/figure>\n\n\n\n

A collaborative study led by the Monash Biomedicine Discovery Institute (BDI) with the Peter Doherty Institute of Infection and Immunity (Doherty Institute), a joint venture of the University of Melbourne and Royal Melbourne Hospital, has shown that an anti-parasitic drug already available around the world kills the virus within 48 hours. <\/h3>\n\n\n\n

The Monash Biomedicine Discovery Institute’s Dr Kylie Wagstaff, who \nled the study, said the scientists showed that the drug, Ivermectin, \nstopped the SARS-CoV-2 virus growing in cell culture within 48 hours.<\/p>\n\n\n\n

“We found that even a single dose could essentially remove all viral \nRNA by 48 hours and that even at 24 hours there was a really significant\n reduction in it,” Dr Wagstaff said.<\/p>\n\n\n\n

Ivermectin is an FDA-approved anti-parasitic drug that has also been shown to be effective in vitro<\/em> against a broad range of viruses including HIV, Dengue, Influenza and Zika virus.<\/p>\n\n\n\n

Dr Wagstaff cautioned that the tests conducted in the study were in vitro<\/em> and that trials needed to be carried out in people.<\/p>\n\n\n\n

“Ivermectin is very widely used and seen as a safe drug. We need to \nfigure out now whether the dosage you can use it at in humans will be \neffective — that’s the next step,” Dr Wagstaff said.<\/p>\n\n\n\n

“In times when we’re having a global pandemic and there isn’t an \napproved treatment, if we had a compound that was already available \naround the world then that might help people sooner. Realistically it’s \ngoing to be a while before a vaccine is broadly available.<\/p>\n\n\n\n

Although the mechanism by which Ivermectin works on the virus is not \nknown, it is likely, based on its action in other viruses, that it works\n to stop the virus ‘dampening down’ the host cells’ ability to clear it,\n Dr Wagstaff said.<\/p>\n\n\n\n

Royal Melbourne Hospital’s Dr Leon Caly, a Senior Medical Scientist \nat the Victorian Infectious Diseases Reference Laboratory (VIDRL) at the\n Doherty Institute where the experiments with live coronavirus were \nconducted, is the study’s first author.<\/p>\n\n\n\n

“As the virologist who was part of the team who were first to isolate\n and share SARS-COV2 outside of China in January 2020, I am excited \nabout the prospect of Ivermectin being used as a potential drug against \nCOVID-19,” Dr Caly said.<\/p>\n\n\n\n

Dr Wagstaff made a previous breakthrough finding on Ivermectin in \n2012 when she identified the drug and its antiviral activity with Monash\n Biomedicine Discovery Institute’s Professor David Jans, also an author \non this paper. Professor Jans and his team have been researching \nIvermectin for more than 10 years with different viruses.<\/p>\n\n\n\n

Dr Wagstaff and Professor Jans started investigating whether it \nworked on the SARS-CoV-2 virus as soon as the pandemic was known to have\n started.<\/p>\n\n\n\n

The use of Ivermectin to combat COVID-19 would depend on the results \nof further pre-clinical testing and ultimately clinical trials, with \nfunding urgently required to keep progressing the work, Dr Wagstaff \nsaid.<\/p>\n","protected":false},"excerpt":{"rendered":"

Ivermectin stops SARS-CoV-2 virus growing in cell culture Date: April 3, 2020 Source 1: Monash University Source 2 : www.sciencedaily.com Summary: A new study has shown that an anti-parasitic drug already available around the world can kill the virus within 48 hours. Scientists found that a single dose of the drug, Ivermectin, could stop the […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[1],"tags":[],"class_list":["post-701","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"aioseo_notices":[],"yoast_head":"\nPossible coronavirus drug identified -<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.potentialloops.org\/?p=701\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Possible coronavirus drug identified -\" \/>\n<meta property=\"og:description\" content=\"Ivermectin stops SARS-CoV-2 virus growing in cell culture Date: April 3, 2020 Source 1: Monash University Source 2 : www.sciencedaily.com Summary: A new study has shown that an anti-parasitic drug already available around the world can kill the virus within 48 hours. 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