Designed antiviral proteins inhibit SARS-CoV-2 in the lab

Computer design of synthetic proteins is creating potent, stable antivirals that block infection at least as well as monoclonal antibodies Date: September 9, 2020 Source 1: University of Washington Health Sciences/UW Medicine Source 2: Summary: Computer-designed miniproteins have now been shown to protect lab-grown human cells from SARS-CoV-2, the coronavirus that causes COVID-19. The […]


Activation of the SARS coronavirus 2 revealed

Infection researchers identify starting points for vaccine development and therapy Date: May 4, 2020 Source 1: Deutsches Primatenzentrum (DPZ)/German Primate Center Source 2: Summary: A viral spike protein mediates entry of SARS-CoV-2 into host cells and harbors an unusual activation sequence. This sequence is cleaved by the cellular enzyme furin and the cleavage is


Key nose cells identified as likely COVID-19 virus entry points

Human Cell Atlas study could help understand transmission of the virus Date: April 23, 2020 Source 1: Wellcome Trust Sanger Institute Source 2: Summary: Two specific nose cell types have been identified as likely initial infection points for COVID-19 coronavirus. Scientists discovered that goblet and ciliated cells in the nose have high levels of

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